Batman (voice of Kevin Conroy) does battle with a rogue's gallery of his most formidable enemies in this DC Comics adventure set in the Arkham universe. Batman has defeated The Riddler (voice of Kevin Conroy) yet again, but when a vital piece of evidence is discovered to be hidden in Arkham Asylum, the Suicide Squad descends upon the notorious sanitarium. Now, with Deadshot (voice of Neil McDonough), Harley Quinn (voice of Hynden Walch), Killer Frost (voice of Jennifer Hale), Captain Boomerang (voice of Greg Ellis), King Shark (voice of John DiMaggio), and Black Spider (voice of Giancarlo Esposito) all teaming up against him, Batman prepares for the fight of his life. Later, when The Joker (voice of Troy Baker) shows up, all hell threatens to break loose.