When a wild pack of dogs carrying the deadly Black Wolf Fever terrorizes a small mining community, only two manage to escape. Van (Shin'ichi Tsutsumi), an acclaimed warrior, and Yuna (Hisui Kimura), a young girl, both try to escape to the countryside and live out their lives peacefully. As the disease starts to make its way across the country, the duo finds themselves in the middle of a massive political conflict. This animated adventure is co-directed by Masashi Ando and Masayuki Miyaji.